The need for controls in case control studies
نویسندگان
چکیده
منابع مشابه
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The authors quantified, first, the effect of misclassified controls (i.e., individuals who are affected with the disease under study but who are classified as controls) on the ability of a case-control study to detect an association between a disease and a genetic marker, and second, the effect of leaving misclassified controls in the study, as opposed to removing them (thus decreasing sample s...
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OBJECTIVE Selecting controls is one of the most difficult tasks in the design of case-control studies. Hospital controls may be inadequate and random controls drawn from the base population may be unavailable. The aim was to assess the use of hospital visitors as controls in a case-control study on the association of organochlorinated compounds and other risk factors for breast cancer conducted...
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A frequently used study design within epidemiology is large cohort studies. In some situations additional information which is not included in the cohort, for instance biological material stored in biobanks, is required. The availability of such material is usually limited and might be very expensive to analyze for the entire cohort. A reasonable strategy is therefore to restrict the study samp...
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ژورنال
عنوان ژورنال: North American Journal of Medical Sciences
سال: 2014
ISSN: 1947-2714
DOI: 10.4103/1947-2714.131252